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c. reduced MC degranulation from the ear pinna in response to local administration of material P by 35% as compared to 9% for saline. Interestingly, a shorter chain NAE, N?acylethanolamines (NAEs), endogenous biologically active lipids including the endogenous cannabinoid receptor ligand anandamide as well as satiety element oleoylethanolamide. PEA
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Of note is the fact, as a result of PEA’s higher lipophilicity, micronized or extremely-micronized formulations are thought being extra simply absorbable, with a lot more favorable pharmacokinetics and greater efficacy. Even though There may be some proof supporting this concept, there remains no proof in the superiority of micronized PEA [16].Th
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